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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
27.88
Human Site:
S497
Identified Species:
47.18
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
S497
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
S497
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S547
Q
R
Q
E
R
I
F
S
K
R
R
G
Q
D
F
Dog
Lupus familis
XP_547295
1021
115999
S534
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
S496
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Rat
Rattus norvegicus
O08874
985
112050
S498
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Q529
R
R
P
R
L
Q
R
Q
K
R
I
F
F
S
K
Chicken
Gallus gallus
XP_422357
1013
114806
S523
Q
R
Q
K
K
I
F
S
K
Q
Q
G
K
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
I490
K
L
Q
R
Q
K
K
I
F
S
K
Q
Q
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N183
Q
C
E
T
C
G
M
N
V
H
K
R
C
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Y256
H
R
F
S
V
H
S
Y
K
R
P
T
F
C
D
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
K348
A
T
W
G
R
L
M
K
R
S
I
P
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
E647
E
A
Y
L
N
F
T
E
G
A
Q
Q
T
A
E
Red Bread Mold
Neurospora crassa
P87253
1142
127954
D599
T
Q
K
K
T
H
K
D
K
A
S
S
M
S
E
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
13.3
100
N.A.
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
40
100
N.A.
40
N.A.
26.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
15
0
0
0
8
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% D
% Glu:
8
0
8
8
0
0
0
8
0
0
0
0
0
0
15
% E
% Phe:
0
0
8
0
0
8
50
0
8
0
0
8
15
0
50
% F
% Gly:
0
0
0
8
0
8
0
0
8
0
0
50
0
8
0
% G
% His:
8
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
8
0
0
15
0
0
0
0
% I
% Lys:
8
0
8
50
43
8
15
8
72
0
15
0
43
0
15
% K
% Leu:
0
8
0
8
8
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
58
8
58
0
8
8
0
8
0
43
50
15
15
8
0
% Q
% Arg:
8
65
0
15
15
0
8
0
8
22
8
8
0
0
8
% R
% Ser:
0
0
0
8
0
0
8
50
0
15
8
8
8
22
0
% S
% Thr:
8
8
0
8
8
0
8
0
0
0
0
8
8
43
0
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _